Advantage II VS Frontline Plus for Dogs

Our dogs are prone to getting infested by small insects like fleas, especially when they often enjoy their time outside. For pet owners, worry not because we can prevent this issue by applying fleas solutions such as Advantage II Vs Frontline Plus for Dogs. These solutions are working effectively and have been proven by countless owners too. If you wonder which of them will work better, let’s see below about what they can offer.

In this comparison, we are going to talk about:

  • How Pet Get Fleas
  • What are Advantage II and Frontline Plus for Dogs
  • How are the Package of Advantage II and Frontline Plus for Dogs
  • What are the Ingredients of Advantage II and Frontline Plus for Dogs
  • What are the Benefit of Advantage II and Frontline Plus for Dogs
  • How are the Efficacy of Advantage II and Frontline Plus for Dogs
  • Advantage II Vs Frontline Plus for Dogs

Fleas on Pets

Our pets can take care of themselves to a certain level but it doesn’t mean we can leave them to do the work alone since there is only so much they can do on their own. Cats for example may not need frequent baths as they are very diligent about grooming their fur and body but we will still need to check whether they are clean enough or whether there is skin and other health issues. Dogs are the same, and in general require more attention when it comes to self-hygiene.

Especially if your pets often roam outside and playing with other pets or animals, it is increasing the chance of them getting infested by small insects like fleas. It may not be a life threatening problem but can lead to serious issues, especially when the skin gets infected from the severe scratching or bites. Our pets like dogs or cats can get infected from other animals while they interact such as when they play in the park or from other pets nearby.

Dogs specifically are often the more social animals than cats and they love to play with other dogs too or investigate open spaces where wild animals may carry fleas. Even when it is just on our daily walk or our backyard, the risk and chance always exist. It may sound surprising but our home can actually be the home of these tiny insects too. They are very small so it is difficult to see and they can get inside our house whether it is from people or pets.

One of two fleas may not sound like a problem but remember that one female fleas can lay up to 40 eggs a day so it will be very quick before we realize that our home is starting to become a fleas nest too. If your pet often visits some facilities such as day care or grooming establishments, do note that this is where many other pets gather too and we never know if at least one of them has fleas and is also infesting somewhere in the facility.

In addition, it has something to do with our current living place too because fleas thrive in a warmer temperature. Fleas are able to survive without a host in this type of climate longer than when the weather is colder. If you often bring your pet to travel, this is also one of the risks we have to pay attention to.

About Advantage II and Frontline Plus for Dogs

Due to their natural presence in wildlife, it is extremely difficult to stay away completely from them as there is even risk when you are at home. While it sounds frightening, pet owners don’t have to worry because it is preventable with the proper solution and maintained hygiene. Fleas can be killed or controlled with insecticide and many are also safe for animals like dogs or cats. We need to apply them routinely, especially when the pet often plays outside.

One application of flea solution can last for about a month so it is convenient to always protect them from these small insects. Advantage II and Frontline Plus for Dogs are some of the most popular solutions that we can rely on. These brands are available almost everywhere so you can find them easily and they do make solutions for both cats and dogs. Especially for cats, it is necessary to buy a specific solution for them since the dog variant can be toxic for our feline friends.

If you have cats too, there are Advantage II Vs Frontline Plus for Cats to choose. This type of solution is applied directly on skin so they can last for longer and in general is more effective compared to flea collars which is also good for prevention but they are typically not as fast acting, especially if your pet is already invested by the insects. These solutions are very easy to use and depending on the brand, they may have different levels of efficacy along with price range.

Both Advantage II and Frontline Plus for Dogs are famous options that pet owners can try when their dogs start to show fleas signs. It can be seen from how they groom or try to scratch their body more often. Sometimes dogs also nibble on their fur when it is extremely itchy and since the bite marks of these insects are uncomfortable, it may cause the pet to become restless. Owners can try to check on their skin and fur while combing or playing routinely to pick a sign as fast as possible.

Advantage II and Frontline Plus for Dogs Package

As a solution that is applied directly on their skin, both Advantage II and Frontline Plus for Dogs are in liquid form, almost like water or essence that we can easily squeeze into their skin. The applicator is very convenient since it is in one dose so one container is for one pet whether it is dogs or cats. They are easy to open and applied with a small tip to prevent the liquid from getting messy. Price wise they are about the same with Frontline Plus being slightly more expensive.

Usually they are available in several doses per box so we can purchase one for a few months ahead. Depending on your dogs, make sure to buy the variant that matches their weight. For example both are available for small, medium, and large dogs but they have different weight ranges that are considered as medium or large. Advantage II medium range is from 11-20 pounds while Frontline Plus for Dogs medium variant is from 22-44 pounds.

Advantage II and Frontline Plus for Dogs Ingredients

When it comes to solutions for almost any health issue, make sure to know what they are made of. The Advantage II and Frontline Plus for Dogs are using a similarly effective ingredients yet they are not the same because Advantage II for dogs use Imidacloprid 9.10% and Pyriproxyfen 0.46% while Frontline Plus for dogs use Fipronil 9.8% and (s)-methoprene 8.8%. The rest of the ingredients are used to mix these ingredients and make the solution easy to apply.

Advantage II and Frontline Plus for Dogs Benefits

In comparison, both Advantage II and Frontline Plus for Dogs are using the same type of insecticide that both kills adult fleas and gets in the way of young or larvae and eggs from developing into adult fleas. Do note that both ingredients have different effects on fleas and the highest consistency is usually meant to kill the adult fleas while the lesser is to help maintain the growth or keep the young and eggs from adulting, as they need to grow first before beginning the reproduction process.

The dosage of each active ingredient are different as designed by the manufacturer but Fipronil tends to work more effectively at the same dosage than Pyriproxyfen as the latter need a higher dose to produce the same effect. Manufacturers can add less or more in their ingredients too, for example Frontline Gold is using both (s)-methoprene and Pyriproxyfen in their formulation which is claimed to be more effective and logically it should too.

Advantage II and Frontline Plus for Dogs Performance

Now for the efficacy, it may vary because there is always mixed reviews among users but it seems for the dog variants Advantage II is more effective at dealing with the fleas. The solution is fast acting and reliable in killing the fleas completely while providing quite the protection too for at least 30 days after application. The solutions are both waterproof and not safe for cats but Frontline Plus for Dogs are also killing ticks in addition to fleas in which the Advantage II is not.

Advantage II Vs Frontline Plus for Dogs

Both Advantage II and Frontline Plus for Dogs are popular options that pet owners can count on to. The efficacy may vary since sometimes they are not working as we hoped for but for most of them time it seems they are pretty useful to help protect the pet from fleas and similar insects. In comparison, Frontline Plus is the solution you want to buy if ticks is also in the problem list. The efficacy is pretty good for both solutions and price wise are about the same.

- Veterinarian-recommended flea treatment for dogs
- Kills multiple flea life stages
- Odorless, waterproof flea prevention for dogs
- Kills through contact. No biting required
- Waterproof flea and tick treatment for dogs: Frontline Plus for Dogs provides waterproof, fast-acting, long-lasting flea and tick treatment and control for your dog. This product is approved for use on dogs 45-88 pounds.
- Break the flea life cycle with frontline: Frontline flea and tick treatment for dogs kills adult fleas plus flea eggs and larvae to stop existing infestations and prevent establishment of new infestations.
- Kills fleas and ticks: Frontline flea and tick treatment for dogs kills fleas, flea eggs, lice, and ticks. This flea and tick treatment kills ticks, including those that may transmit Lyme disease.
- Trusted flea and tick protection for dogs: Frontline has been trusted by veterinarians for nearly 20 years. Made with 2 tough killing ingredients, fipronil and (S)-methoprene – one to kill adult fleas and ticks and the second to kill flea eggs and larvae – this fast-acting, long-lasting protection provides flea and tick control for dogs and puppies 8 weeks and older.


The decision is all yours since sometimes these solutions are not as easily available in all places. We do recommend trying Advantage II for dogs because it seems to work more effectively and also has a higher customer satisfaction while often being cheaper too. But, if your dog also has ticks, Frontline Plus is the more ideal choice.